Real-World Data Drives CAR T Treatment Decisions, Reveals Benefits of Earlier Administration | AMCP Nexus 2025 | Managed Healthcare Executive

Real-World Data Drives CAR T Treatment Decisions

Payers and providers are using real-world data to identify high-performing treatment centers, reduce administrative bottlenecks, and support value-based contracting arrangements.

In 2017, the first two CAR T-cell therapies - Kymriah (tisagenlecleucel) and Yescarta (axicabtagene ciloleucel) - were approved and have helped to transform treatment for blood cancer.

Since then, the two therapies have been approved for additional indications and five new CAR T-cell therapies have come to market.

As the CAR T pipeline expands into solid tumors and autoimmune diseases, the current infrastructure may struggle to meet increased demand.

Author summary: Real-world data informs CAR T treatment decisions.

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Managed Healthcare Executive Managed Healthcare Executive — 2025-10-29

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