Imfinzi Regimen Demonstrates 22% Survival Benefit in Early Gastric and GEJ Cancer | Applied Clinical Trials Online

Imfinzi Regimen Demonstrates Survival Benefit in Early Gastric and GEJ Cancer

The Phase III MATTERHORN trial has shown a 22% reduction in the risk of death for patients with early-stage gastric and gastroesophageal cancers.

Nancy Ghattas, VP, US Oncology Commercial Franchise Head of Immuno-Oncology at AstraZeneca, discussed the trial's results, highlighting the Imfinzi-based perioperative regimen's ability to improve overall survival regardless of PD-L1 status.

The Imfinzi-based perioperative regimen demonstrated a 22% reduction in the risk of death and improved overall survival.

This marks the first immunotherapy in this setting to show such benefit, redefining outcomes for patients with early-stage gastric and gastroesophageal cancers.

Author's summary: Imfinzi regimen shows 22% survival benefit.

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Applied Clinical Trials Online Applied Clinical Trials Online — 2025-10-29

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