Dr. LK Medina-Kauwe developed a bioengineered delivery system to treat resistant and metastatic tumors, highlighting nano-bioparticles.
Repurposing parts of viruses, growth factors, and nucleic acid-binding proteins has led to the development of a bioengineered therapeutic delivery vehicle being evaluated as a cancer-specific molecular missile.
Dr LK Medina-Kauwe combined the cell-binding, membrane-penetration, and intracellular trafficking functions of pathogen proteins and naturally occurring protein ligands to develop a biologically based tumor-homing platform technology designed to self-assemble with and selectively deliver therapeutic molecules to resistant and metastatic tumors.
These molecular missiles are comprised of nano-sized biologically derived particles, or nano-bioparticles (NBPs).
Author summary: Targeted nanotherapy fights cancer with nano-bioparticles.