Molecular laser tag: identifying chromosomal abnormalities with AI

Molecular Laser Tag: Identifying Chromosomal Abnormalities with AI

Researchers have developed an AI-assisted technology to identify and tag chromosomal abnormalities in cells, according to a story from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany.

An AI tool uses a game of molecular 'laser tag' to identify cells that can shed light on the earliest origins of cancer.

The human body relies on precise genetic instructions to function, and cancer begins when these instructions get scrambled. When cells accumulate genetic errors over time, they can break free of normal controls on their growth and divide excessively.

Chromosomal abnormalities, including numerical and structural defects in chromosomes, are a common first step in this process, often contributing to normal cells turning cancerous.

A new AI tool developed by researchers in the Korbel Group at EMBL now offers a powerful method to gain deep insights into how such chromosomal abnormalities arise.

Author's summary: AI-assisted technology for identifying chromosomal abnormalities.

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BioTechniques BioTechniques — 2025-10-29

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